Read e-book online Nuclear Magnetic Resonance of Paramagnetic Macromolecules PDF

By Claudio Luchinat, Mario Piccioli (auth.), Gerd N. La Mar (eds.)

ISBN-10: 0792327675

ISBN-13: 9780792327677

ISBN-10: 0792331966

ISBN-13: 9780792331964

ISBN-10: 0792333470

ISBN-13: 9780792333470

ISBN-10: 9048145228

ISBN-13: 9789048145225

ISBN-10: 9401585733

ISBN-13: 9789401585736

Since A. Kowalsky's first document of the spectrum of cytochrome c in 1965, curiosity within the detection, task and interpretation of paramagnetic molecules has surged, particularly within the final decade.
periods of structures have performed a key position within the improvement of the sector: heme proteins and iron-sulfur proteins. those structures are distinct in lots of respects, one in every of that's that they include well-defined chromophores, each one of that are studied intimately outdoors the protein matrix. they're the main effectively studied macromolecules, and the 1st 8 and final six of the seventeen contributions to this e-book care for heme and/or iron-sulfur proteins. the center 3 chapters survey the development on, and demanding promise of, tougher platforms which don't own a chromophore, yet that have however yielded awesome insights into their constitution.

Show description

Read or Download Nuclear Magnetic Resonance of Paramagnetic Macromolecules PDF

Best nuclear books

Download e-book for iPad: Chiral Dynamics: Theory and Experiment by Aron Bernstein, Dieter Drechsel, Thomas Walcher

During this quantity, experimentalists and theoreticians speak about which experiments and calculations are had to make major development within the box and in addition how experiments and theoretical descriptions could be in comparison. the subjects taken care of are the electromagnetic creation of Goldstone bosons, pion--pion and pion--nucleon interactions, hadron polarizability and shape components.

New PDF release: Perspectives on Sino-American Strategic Nuclear Issues

Sino-American nuclear kin are severe given ongoing modernization efforts on each side and an more and more complicated local and international nuclear environment.  This quantity pairs chinese language and American authors jointly to provide nationwide views on modern nuclear matters, together with perceptions of strategic context, nationwide safety priorities, doctrines, perceptions of local threats, and techniques to deal with those hazards.

Nuclear Models - download pdf or read online

This reprint has been approved through Springer-Verlag on the market in Africa, Middle/South the US, Israel, Jordan, Lebanon, Saudia-Arabia, Syria, South-East-Asia and China simply

Extra info for Nuclear Magnetic Resonance of Paramagnetic Macromolecules

Example text

62], with permission) 42 The active site of cobalt-substituted superoxide dismutase is shown in Fig. 7[67-69]. In this case we have a copper(II) (S=l/2) and a high spin (S=3/2) cobalt(II) coupled. antiferromagnetically susceptibility Magnetic measurements have shown that J= 33 cm-1 [70]. The coupling energy is therefore small compared to kT, so that at room temperature all the magnetically almost coupled equally levels populated. are The Figure 7. Schematic drawing of the metal sites in superoxide dismutase.

An NMR investigation of the thiocyanate adduct of the cobalt(II)-substituted human carbonic anhydrase II, J. Magn. Reson. in press 26 45. S. W. G.. 291. 46. , Monnanni, R. and Scozzafava, A (1985) Investigation of Cu2Co2SOD and its anion derivatives. 1H NMR and electronic spectra, J. Am. Chem. Soc. 107, 4391-4396. 47. , Luchinat, C. and Piccioli, M. (1994) Copper zinc superoxide dismutase a paramagnetic protein that provides a unique frame for the NMR investigations, Progr. Nucl. Magn. Reson. Spectrosc.

For protons in paramagnetic molecules Curie spin relaxation is the only sizable form of chemical shift anisotropy. 15 CDC A t 2 • 0 c 21 2H 200 400_ t ... 0 11 eoo 11 11 800 ppm ppm 60 40 20 ppm 40 60 20 ppm 60 40 20 6 1'HI Figure 10. 15N_lH HMQC experiments performed on (A) anion-free Cu 2co2 SOD, (B) Cu 2 co2 SOD+N 3 -, (C) Cu 2 co 2SOD+CW. 15 N enriclunent was about 98%. The experiments were performed in magnitude mode, using the four pulse sequence described by Bax et al. [53). The delay between the first two pulses was set to match the T2 values of the proton signals (I.

Download PDF sample

Nuclear Magnetic Resonance of Paramagnetic Macromolecules by Claudio Luchinat, Mario Piccioli (auth.), Gerd N. La Mar (eds.)

by Joseph

Rated 5.00 of 5 – based on 30 votes