Read e-book online Nuclear and particle astrophysics PDF

By Hirsch J.G., Page D. (eds.)

ISBN-10: 052163010X

ISBN-13: 9780521630108

What's the Universe made up of? How previous is it? How does a supernova explode? will we notice black holes? And the place do cosmic rays originate? This quantity offers a finished and pedagogical creation to trendy rules and demanding difficulties in nuclear and particle astrophysics. Articles written by means of 8 best specialists conceal a wealth of fascinating themes. jointly, they current the Universe as a laboratory for checking out state of the art physics. This well timed quantity effectively bridges the space among convention complaints and really good monographs. It presents a useful source for graduate scholars and energetic researchers in nuclear and particle physics, astrophysics and cosmology.

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However, this is not a universal phenomenon. , 2010). 1, which is implicated in ASD with macrocephaly. , 2010). This is not restricted to neurodevelopmental disorders, as the most common locus affected in CharcotMarie-Tooth (CMT) neuropathy, PMP22, when deleted causes a different neurological phenotype to that associated with gene gain (Chance, 2006). Duplication of PMP22 leads to CMT type 1A, while PMP22 deletion leads to a disease known as hereditary neuropathy with liability to pressure palsies (HNPP).

The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseases. Genes Dev, 15(1):15-23. Lenski C, Kooy RF, Reyniers E, Loessner D, Wanders RJ, et al. (2007). The reduced expression of the HADH2 protein causes X-linked mental retardation, choreoathetosis, and abnormal behavior. Am J Hum Genet, 80(2):372-7. Lesage S, Brice A. (2009). Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum Mol Genet, 18(R1):R48-59. Lewis DA, Levitt P. (2002). Schizophrenia as a disorder of neurodevelopment.

2004). Dynamics of cancer progression. Nat Rev Cancer, 4(3):197-205. Midic U, Oldfield CJ, Dunker AK, Obradovic Z, Uversky VN. (2009). Protein disorder in the human diseasome: unfoldomics of human genetic diseases. BMC Genomics, 10(Suppl 1):S12. Miller MP, Kumar S. (2001). Understanding human disease mutations through the use of interspecific genetic variation. Hum Mol Genet, 10(21):2319-28. Minshew N, McFadden K. Commentary for special issue of autism research on mouse models in ASD: a clinical perspective.

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Nuclear and particle astrophysics by Hirsch J.G., Page D. (eds.)

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