Get Mouse models of the nuclear envelopathies and related PDF

By Colin Stewart

ISBN-10: 012397920X

ISBN-13: 9780123979209

ISBN-10: 0123984645

ISBN-13: 9780123984647

ISBN-10: 1306881021

ISBN-13: 9781306881029

Quantity 109 of Current subject matters in Developmental Biology covers mouse types of the nuclear envelopathies and similar ailments, with contributions from a world board of authors. The chapters offer a complete set of reports protecting such subject matters as mouse versions neurodegenerative ailments together with Parkinson's and dystonia, muscle getting old and sarcopenia, cardiac failure and service, getting older and customers lifespan extension, lipodystrophy and the importance in fats rules, additionally making a choice on developmental mutations in mammals and nuclear envelope and LINC advanced in disease.

  • Covers the realm of mouse versions of developmental genetic disease
  • International board of authors
  • Provides a accomplished set of stories protecting such subject matters as mouse types neurodegenerative ailments together with Parkinson's, muscle getting older, lipodystrophy, and more

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A. (2010). Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence. Journal of Cell Science, 123, 2605–2612. Bergo, M. , Schmidt, W. , Kendall, L. , et al. (2002). Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect. Proceedings of the National Academy of Sciences of the United States of America, 99, 13049–13054. Bertrand, A. , et al. (2012). DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death.

2012). DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death. Human Molecular Genetics, 21, 1037–1048. Bickmore, W. A. (2013). The spatial organization of the human genome. Annual Review of Genomics and Human Genetics, 14, 67–84. , et al. (1994). Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy. Nature Genetics, 8, 323–327. , Di Barletta, M. , Becane, H. , Hammouda, E. , et al.

Et al. (2013). Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria. Science, 340, 1330–1333. , Ng, J. , Young, S. , & Osada, S. (2006). Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling. Development, 133, 3919–3928. , Gonzalez, J. , Sanz-Gonzalez, S. , O’Connor, J. , et al. (2006). A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C. Genes & Development, 20, 307–320.

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Mouse models of the nuclear envelopathies and related diseases by Colin Stewart


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