Managing Gastrointestinal Complications of Diabetes - download pdf or read online

By Joseph Sellin

ISBN-10: 3319486616

ISBN-13: 9783319486611

ISBN-10: 3319486624

ISBN-13: 9783319486628

An perfect scientific guide for doctors that frequently deal with sufferers with diabetes and comorbid gastrointestinal issues. The concise structure offers evidence-based content material with a certain emphasis on analysis, as as much as seventy five% of sufferers traveling diabetes clinics document major gastrointestinal signs. comprises directions for hardship prevention, remedy, and long term illness management.

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Extra info for Managing Gastrointestinal Complications of Diabetes

Example text

Changes in gastric emptying may affect postprandial blood glucose concentrations, because of unpredictable delivery of food. 1 Therapeutic pyramid for diabetic gastroparesis. Starting at the base, patients with mild symptoms can be managed with glycemic control and dietary modifications. The peak of the pyramid represents the minority of patients that do not respond to therapy, and therapeutic options are limited and not necessarily evidence based (Reproduced with permission from Sellin [17] ©Nature) Chapter 3.

Acupuncture, electroacupuncture, and acupressure stimulation of specific pressure points have been used for symptom relief. A meta-analysis of 14 randomized controlled studies showed that acupuncture had significantly improved dyspeptic symptoms (including nausea, vomiting, loss of appetite, and stomach fullness) compared with a control group, despite there being no difference in solid gastric emptying [45]. However, these studies were of low quality with a high risk of bias, and large-scale high-quality randomized clinical trials are needed.

However, the incidence of SIBO in patients with DM and diarrhea is much higher, approaching closer to 50 % in one study [20]. The pathology of SIBO is related to decreased acid in the stomach (acid decreases overall bacterial burden), abnormal gastrointestinal motility and slow transit (leads to stasis of intestinal contents and subsequent bacterial overgrowth), or structural abnormalities from surgeries, particularly blind loops, may also create reservoirs that enable overgrowth of bacteria. DM is known to cause gastroparesis and abnormal intestinal motility.

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Managing Gastrointestinal Complications of Diabetes by Joseph Sellin


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