By H. Watanabe, J. R. Jass, L. H. Sobin (auth.)
This can be the revised variation of the WHO histological class of oesophageal and gastric tumours. It displays the $64000 adjustments that haveoccurred because the first version within the fields of lymphomas, endocrine tumours and the dysplasias in addition to including a few newly describedentities. it units the foreign commonplace for the following decade.
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Additional resources for Histological Typing of Oesophageal and Gastric Tumours
They are typically positive for S100 protein immunohistochemically. 1 Neurilemmoma (Schwannoma) (Figs. 3 Granular eeli Tumour This usually occurs in the submucosa. 1 Leiomyosareoma (Fig. 88) This is the most common malignant soft tissue tumour of the stomach. It can be vascular, haemorrhagic, necrotic, cystic and ulcerated, and so its appearance is frequently altered by these changes. The tumour may present as a large cystic mass within the abdominal cavity, connected to the wall of the stomach by a narrow pedicle.
High-grade lymphomas mainly comprise large B-cell tumours. 34 Definitions and Explanatory Notes 5 Miscellaneous Tumours The very rare oeeurrenee of teratoma, eareinosareoma and malignant melanoma of the stomaeh has been described. 96) A benign sessile or peduneulated polyp eomposed of irregular hyperplastie glands, the epithelium being mostly of the foveolar (i. e. superficial gastrie) type, but pylorie (antral) glands, ehief eelis and parietal eelis may be present; regenerative atypia in the epithelium (immature regenerating epithelium) and atypieal reaetive stromal eelis may appear frequently after erosion.
1 Giant Rugal Hypertrophy (Menetrier Disease) (Figs. 107 - 109) Thiekened fundie type mueosa, initially with balaneed mueosal hyperplasia and later with fundie gland atrophy, pseudopylorie gland metaplasia (or mueous neek eell hyperplasia), eystie ehange in the deep mueosa and relative elongation of foveolae and finally with widening of superjiciallamina propria and erosion. These ehanges oeeur in a diffuse or a loealized form. This should be distinguished from other hypertrophie rugal lesions or superfieial gastritis with severe inflammatory infiltrates of the fundie mueosa.
Histological Typing of Oesophageal and Gastric Tumours by H. Watanabe, J. R. Jass, L. H. Sobin (auth.)