By Peter J. Dunn, Andrew Wells, Michael T. Williams
Edited by way of 3 of the world's top pharmaceutical scientists, this is often the 1st booklet in this vital and sizzling subject, containing a lot formerly unpublished info. As such, it covers all points of eco-friendly chemistry within the pharmaceutical undefined, from basic molecules to advanced proteins, and from drug discovery to the destiny of prescription drugs within the atmosphere. in addition, this prepared reference includes a number of convincing case reports from undefined, similar to Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary technique has yielded effective and environmentally-friendly tactics. ultimately, a bit on expertise and instruments highlights the benefits of eco-friendly chemistry.
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Additional info for Green Chemistry in the Pharmaceutical Industry
In general, a combination of volume per unit of time and/or energy would be a most useful metric, but one should also consider these materials in terms of their intrinsic hazards, just as for any process reagent, solvent, or reactant. 3 Life Cycle Assessment (LCA) Solvent D A + B ⎯⎯⎯⎯⎯→ C Consider the simple reaction presented above. The environmental impacts of this reaction are not only the ones associated with the use of A, B, and D in the process, but also the ones associated with the production of the materials and energy required to produce A, B, and D as well as the impacts associated with the treatment and disposal of any waste derived from the process.
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A. 1039/b919115c. A. (1993) Chirotechnology: Industrial Synthesis of Optically Active Compounds, Marcel Dekker, New York, pp. 47–61. A. (2008) Chem. , 3352–3365. A. , 9, 1273–1283. M. (2008) PNAS, 105, 13197–13202. Y. , 9, 411–420. T. (2006) Org. Biomol. , 4, 2337–2347. 21 2 Green Chemistry Metrics Richard K. C. 1 Introduction The development of the green chemistry movement has challenged chemists and engineers in all ﬁelds to consider the environmental impact of a chemistry process as an integral part of its development program.
Green Chemistry in the Pharmaceutical Industry by Peter J. Dunn, Andrew Wells, Michael T. Williams