By Nicole C. Panarelli
Frozen sections are played whereas a sufferer is present process surgical procedure as a foundation for making an instantaneous prognosis that might influence remedy judgements. Frozen part prognosis is usually a hugely difficult state of affairs for the pathologist who needs to render a prognosis fast for the sufferer and surgeon.The Frozen part Library sequence will supply concise, trouble-free, website particular handbooks which are well-illustrated and spotlight the pitfalls, artifacts, and differential prognosis matters that come up within the moved quickly frozen part state of affairs. Nicole C. Panarelli, MD is affiliated with Weill clinical collage of Cornell collage, big apple, new york and ny Presbyterian health center, manhattan, manhattan. Rhonda okay. Yantiss, MD is affiliate Professor of Pathology and Laboratory drugs at Weill clinical collage of Cornell collage, big apple, NY.
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Additional resources for Frozen Section Library: Appendix, Colon, and Anus
Microscopic Features of Colorectal Carcinoma Infiltrative cancers may be associated with apparent dysplasia overlying the tumor, however, one should be cautious when regarding this finding as a “hard” criterion for a primary malignancy, since colonization of the basement membrane may simulate the appearance of an in situ lesion, as described below (Fig. 3). Most colorectal adenocarcinomas consist of infiltrating single, or cribriform, glands with luminal necrosis and lack architectural heterogeneity (Fig.
13 Metastatic diffuse-type gastric cancers often contain signet ring cells, which are quite uncommon in primary colonic carcinomas (a). Mammary carcinomas show mild cytologic atypia and a lobular growth pattern (b) Non-neoplastic Processes That Mimic Malignancy 47 Fig. 14 Metastatic melanoma typically invades the colonic mucosa and infiltrate between colonic crypts. Melanoma cells contain abundant cytoplasm and large nuclei with prominent nucleoli (a). In contrast, diffuse-type colorectal carcinomas show high-grade cytologic features and harbor foci of cellular necrosis (b) 48 3 Metastases and Mimics of Colorectal Carcinoma Non-neoplastic Processes That Mimic Malignancy 49 Fig.
Pediatr Hematol Oncol 24(4):281–289 References 33 4. Kondi-Pafiti AI, Grapsa DS, Kairi-Vasilatou ED, Voros DK, Smyrniotis VE (2006) “Solitary necrotic nodule of the liver”: an enigmatic entity mimicking malignancy. Int J Gastrointest Cancer 37(23):74–78 5. Kroncke TJ, Taupitz M, Kivelitz D, et al (2000) Multifocal nodular fatty infiltration of the liver mimicking metastatic disease on CT: imaging findings and diagnosis using MR imaging. Eur Radiol 10(7):1095–1100 6. Ryan RS, Al-Hashimi H, Lee MJ (2001) Hepatic abscesses in elderly patients mimicking metastatic disease.
Frozen Section Library: Appendix, Colon, and Anus by Nicole C. Panarelli