Download e-book for iPad: Drug Delivery: Principles and Applications by Binghe Wang, Longqin Hu, Teruna J. Siahaan

By Binghe Wang, Longqin Hu, Teruna J. Siahaan

ISBN-10: 1118833368

ISBN-13: 9781118833360

Following its winning predecessor, this e-book covers the basics, supply routes and cars, and functional purposes of drug supply. within the second variation, just about all chapters from the former are retained and up to date and several other new chapters additional to make a extra whole source and reference.

• Helps readers comprehend growth in drug supply examine and applications
• Updates and expands insurance to mirror advances in fabrics for supply autos, drug supply techniques, and therapeutics
• Covers contemporary advancements together with transdermal and mucosal supply, lymphatic procedure supply, theranostics
• Adds new chapters on nanoparticles, managed drug unencumber platforms, theranostics, protein and peptide medications, and biologics delivery

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Wiley‐ VCH: Weinheim, Germany, 2006, pp 45–91. ; Wagner, C. Curr. Opin. Mol. Ther. 2003, 5(2), 172–179. 42. Brambell, F. W. ; Morris, I. G. Nature 1964, 203(4952), 1352–1355. 43. ; Mascelli, M. A. Ann. Rev. Pharmacol. Toxicol. 2011, 51, 359–372. 44. ‐M. AAPS J. 2009, 11(2), 300–306. Morgan, E. ; Goralski, K. ; et al. Drug Metab. Dispos. 2008, 36(2), 205–216. Nolting, B. Methods. Mol. Biol. 2013, 1045, 71–100. Eliceiri, B. ; Cheresh, D. A. J. Clin. Invest. 1999, 103, 1227–1230. Miller, W. ; Alberts, D.

2 provides, for example, thinking paths in addressing an issue for oral bioavailability. The discussions are further pro­ jected into several of later chapters on controlled target‐specific drug delivery (Chapters 15–22). Targeting specific organ or tumor tissues through different technologies and potential personalized drug delivery are discussed in Chapters 17–22. Several chapters provided a number of technical approaches to improve drug delivery. Physicochemical approaches by formulation include controlled release (Chapter 15), prodrug approaches (Chapter 12), liposome vehicles (Chapter 13), and nanoparticles (Chapter 14).

Development of pharmacokinetics and pharmacodynamics relationship by mathe­ matical modeling of the interactions of a drug molecule with the entire biological system is important to the prediction of drug concentrations in the systemic circulation, and, therefore, the pharmacological responses. Better understanding of the system will 14 Factors that Impact the Developability of Drug Candidates allow a pharmaceutical scientist to utilize the system and manipulate the system for the pur­pose of drug delivery.

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Drug Delivery: Principles and Applications by Binghe Wang, Longqin Hu, Teruna J. Siahaan

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