By Eric Francotte, Wolfgang Lindner, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Chapter 1 Chiral medicines from a old perspective (pages 1–26): Joseph Gal
Chapter 2 Stereoselective Synthesis of substances – An business viewpoint (pages 27–65): Hans?Jurgen Federsel
Chapter three facets of Chirality in common items Drug Discovery (pages 67–94): Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt and Ansgar Schuffenhauer
Chapter four Biotransformation tools for getting ready Chiral medicines and Drug Intermediates (pages 95–123): Michael Muller and Marcel Wubbolts
Chapter five solution of Chiral medicines and Drug Intermediates by way of Crystallisation (pages 125–154): Kazuhiko Saigo and Kenichi Sakai
Chapter 6 Isolation and construction of Optically natural medicines via Enantioselective Chromatography (pages 155–187): Eric Francotte
Chapter 7 Stereoselective Chromatographic equipment for Drug research (pages 189–260): Norbert M. Maier and Wolfgang Lindner
Chapter eight Capillary Electrophoresis Coupled to Mass Spectrometry for Chiral medicinal drugs research (pages 261–281): Serge Rudaz and Jean?Luc Veuthey
Chapter nine strong Chiral Molecular instruments for practise of Enantiopure Alcohols and Simultaneous decision in their Absolute Configurations via X?Ray Crystallography and/or 1H NMR Anisotropy equipment (pages 283–321): Nobuyuki Harada
Chapter 10 key phrases in Chirality Modeling: Molecular Modeling of Chirality – software program and Literature learn on Chirality in Modeling, Chirality in Docking, Chiral Ligand–Receptor interplay and Symmetry (pages 323–340): Gerd Folkers, Mine Yarim and Pavel Pospisil
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Additional resources for Chirality in Drug Research, Volume 33
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1853, 37, 166–167. 39 L. Pasteur, Compt. Rend. Acad. Sci. 1848, 34, 535–538. T. Kelvin, J. Oxford Univ. Jr. Sci. Club 1894, No. 18, 25. 41 L. Pasteur, Ann. Chim. Phys. 1850, 3e sér. 28, 56–99. 42 J. L. Gay-Lussac, Schweigger’s J. 1826, 48, 381. -B. Biot, Ann. Chim. Phys. 1838, 69, 22. 44 L. Pasteur, Compt. Rend. Acad. Sci. 1853, 36, 19–26. 45 L. Pasteur, Compt. Rend. Acad. Sci. 1853, 37, 110–114. 46 L. Pasteur, Recherches sur la Dissymétrie Moléculaire des Produits Organiques Naturels, in Leçons de chimie professées en 1860 par MM.
Chirality in Drug Research, Volume 33 by Eric Francotte, Wolfgang Lindner, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers