By Charles R. Thomas MD, Clifton D. Fuller MD
Biliary Tract and Gallbladder melanoma: analysis and treatment is a entire and definitive dialogue of all facets of the remedy of malignant tumors of the gallbladder and biliary tract. this can be the 1st publication to check those cancers in such intensity, as quick advances in surgical oncology and radiotherapeutic techniques have demanded the complete insurance this article provides.The publication progresses logically, with early chapters proposing the epidemiologic, pathologic, and pathogenetic features of BT and GB lesions, by means of first-class discussions of scientific and radiologic prognosis and staging. ultimately, the entire arsenal of healing techniques is gifted, from the neighborhood to systemic, proven to experimental. Segments all through aspect the most up-tp-date state-of-the-art treatments, making the most recent info on hand throughout a couple of subdisciplines.Features of this precise textbook include:An particular and complete concentrate on neoplasms of the gallbladder and biliary tractA multidisciplinary concentration, with contributions from clinical, surgical, and radiation oncology, pathology, and imaging, and a transparent emphasis on team-based techniques to oncologic careThe most up-to-date scientific examine and remedy discussions from foreign expertsBiliary Tract and Gallbladder melanoma serves because the single-source wisdom base for multidisciplinary biliary tract melanoma administration. it really is complete adequate to illustrate new remedies of biliary tract melanoma to skilled practitioners, but concise adequate to function an advent to newbies within the box. (20100503)
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Additional info for Biliary Tract and Gallbladder Cancer: Diagnosis & Therapy
Am J Gastroenterol 1986; 81:76-79. 254. Lim MK, Ju YH, Franceschi S, et al. Clonorchis sinensis infection and increasing risk of cholangiocarcinoma in the Republic of Korea. Am J Trop Med Hyg 2006; 75:93-96. 255. Choi D, Lim JH, Lee KT, et al. Cholangiocarcinoma and Clonorchis sinensis infection: a case-control study in Korea. J Hepatol 2006; 44:1066-1073. 256. Kim HJ, Yun SS, Jung KH, et al. Intrahepatic cholangiocarcinoma in Korea. J Hepatobiliary Pancreat Surg 1999; 6:142148. 257. Jain RV, Mills PK, Parikh-Patel A.
ErbB2 transgenic mice. In addition, we have found elevated levels of COX-2/PGE2 and elevated activity of Akt, mitogen-activated protein kinase (MAPK), and mammalian target of rapamycin (mTOR) in the GBC from these mice. These molecular alterations are similar to those reported in human GBC or BTC. In this chapter we will discuss the role of growth factors and their receptors (receptor tyrosine kinases, RTKs), downstream signaling pathways of these RTKs, and inflammatory mediators during gallbladder carcinogenesis.
3. Malik IA. Gallbladder cancer: current status. Expert Opin Pharmacother 2004; 5:1271-1277. 4. Misra S, Chaturvedi A, Misra NC. Gallbladder cancer. Curr Treat Options Gastroenterol 2006; 9:95-106. 5. Moerman CJ, Bueno-de-Mesquita HB. The epidemiology of gallbladder cancer: lifestyle related risk factors and limited surgical possibilities for prevention. Hepatogastroenterology 1999; 46:1533-1539. 6. Pandey M, Shukla VK. Diet and gallbladder cancer: a casecontrol study. Eur J Cancer Prev 2002; 11:365-368.
Biliary Tract and Gallbladder Cancer: Diagnosis & Therapy by Charles R. Thomas MD, Clifton D. Fuller MD