By M.A. Barocchi, J.L. Telford
Bacterial pili play vital roles as environmental sensors, in host colonization and in biofilm formation, allowing micro organism to engage with the surroundings, with surfaces and with different micro organism and host cells. such a lot micro organism, either Gram confident and Gram detrimental, and just about all bacterial pathogens, are piliated. This booklet discusses the synthesis, constitution, evolution, functionality and function in pathogenesis of those advanced constructions, and their foundation for vaccine improvement and therapeutics for Streptococcus pathogens. it truly is a useful source for researchers and scholars of clinical microbiology.
Read Online or Download Bacterial Pili: Structure, Synthesis and Role in Disease PDF
Similar nonfiction_12 books
George T. Hunt’s vintage 1940 research of the Iroquois in the course of the heart and overdue 17th century offers war due to depletion of common assets within the Iroquois place of origin and tribal efforts to imagine the position of middlemen within the fur alternate among the Indians to the west and the Europeans.
The LNCS magazine Transactions on Large-Scale information- and Knowledge-Centered platforms makes a speciality of info administration, wisdom discovery, and information processing, that are center and sizzling issues in machine technological know-how. because the Nineties, the web has turn into the most driver at the back of program improvement in all domain names.
- Foundations of measurement, vol.3: representation, axiomatization, and invariance
- Command decisions
- Creating second lives : community, identity, and spatiality as constructions of the virtual
- Report Writing for Architects
- Production of Biofuels and Chemicals with Microwave
Additional resources for Bacterial Pili: Structure, Synthesis and Role in Disease
These pili are typically ~9 nm and flexible, range in length up to 1 micron, and dynamically extend and retract (Fig. 2A). The P-type pili by contrast are thicker (9–11 nm), more rigid, and much shorter than F-pili, although length measurements are complicated by the fact that isolated pili are typically broken (Fig. , 1980, Bradley, 1980; Paranchych and Frost, 1988). A third type of pilus-based transfer system that also has been extensively characterized is encoded by the IncI plasmids, as represented by Pseudomonas aeruginosa plasmid R64.
The P- and F-type systems thus share a common ancestry and VirB-mediated architectural and functional features. The F-type systems, however, also are more complex than P-type systems by virtue of having acquired additional novel domains and protein subassemblies during evolution (Fig. 3C). These systems, for example, code for an outer membrane protein designated TraN. TraN family proteins are large (~600–1200 residues) cysteine-rich proteins thought to function as adhesins for formation of stable donor–recipient cell mating pairs.
M. (2004) An active type IV secretion system encoded by the F plasmid sensitizes Escherichia coli to bile salts. Journal of Bacteriology 186, 5202–5209. E. (1980) Morphological and serological relationships of conjugative pili. Plasmid 4, 155– 169. E. R. (1980) Specification of surface mating systems among conjugative drug resistance plasmids in Escherichia coli K-12. Journal of Bacteriology 143, 1466–1470. C. Jr (1971) The properties of sex pili, the viral nature of ‘conjugal’ genetic transfer systems, and some possible approaches to the control of bacterial drug resistance.
Bacterial Pili: Structure, Synthesis and Role in Disease by M.A. Barocchi, J.L. Telford